Scroll to Section:
When memorable experiences occur, a particular subset of neurons is activated in the brain. In this video, ALESSIO ATTARDO analyzes how these engram neurons are created. Imaging the synapse network through which neurons connect and communicate, Attardo is able to identify distinctions between those that go on to become engram neurons and those which do not. Focusing on the hippocampus, this work calls into question existing research on the neocortex by suggesting that animals with less stable connectivity tend to be better at learn and recall. Helping us to better understand the neurological processes involved in memory formation, the research has clear applications for the treatment of people who suffer deficiencies in this area.
DOI:
https://doi.org/10.21036/LTPUB10918
Institution
Max Planck Institute for Psychiatry
Das Ziel des Max-Planck-Instituts für Psychiatrie ist es, durch eine einzigartig enge Verbindung von Grundlagenforschung, klinischer Forschung und Patientenversorgung neue Erkenntnisse über die Ursachen von psychiatrischen Erkrankungen zu gewinnen und in neue diagnostische Möglichkeiten und Behandlungs- sowie Präventionsansätze umzuwandeln. Stress- und Trauma bedingte Erkrankungen wie Depression und Angsterkrankungen bilden den Schwerpunkt unserer Forschung und unserer klinischen Behandlungsangebote.
Original publication
Hippocampal Neurons with Stable Excitatory Connectivity Become Part of Neuronal Representations
PLoS biology
Published in 2020
Reading recommendations
Labelling and Optical Erasure of Synaptic Memory Traces in the Motor Cortex
Nature
Published in 2015
Memory Engrams: Recalling the Past and Imagining the Future
Science
Published in 2020
Beyond
A Ground-breaking Scientific Revolution
An Alarming Challenge for Society
If I Had a Second Life
A Personal Reading Recommendation
